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Does not prevent Isaac from taking contact damage. Bombs, hearts, keys, coins, pills, batteries or tarot cards. Unlock this item by beating the Depths 20 times and killing the Gish boss. Unlock this item by collecting two of the following items: You may see more or less than this on the Found HUD overlay, however this number varies based on your other damage increasing items.
The Fallen boss pulls items from the Devil Room Pool. Blue Baby, The Lost. In Afterbirth this item synergises with Brimstone and Tech, allowing them to do more damage the further away the enemy is.
After picking up a coin he has a random chance to drop pickups, including hearts, keys, bombs, coins, pills, cards or trinkets. In Afterbirth this is one of the 3 items required to create the Super Bum familiar transformation. If your speed stat is already higher then that value is still used. Unlock this item by collecting 3 Guppy items and transforming into Guppy. In Afterbirth this item gives a random tear effect every few seconds, not every room.
Unlike the Cube of Meat, it does not block enemy shots. In Afterbirth this orbital can now block shots, making it equal to the Cube of Meat. After which, the only way to access an Angel Room is via the Sacrifice Room. In Afterbirth this is no longer a Special Item and the slowing effect only activates for one room after taking damage.
See the dedicated Devil room page for more details. Unlock this item by picking up 2 of the following items: However with lasers such as Brimstone this point is no longer true.
If the heart is hit, Isaac will take damage. This effect does not happen until you get a new orbital after Big Fan. Mulligan can be hit by enemy projectiles, making him a good shield. When the pool is empty, it will eventually re-roll all your items into heart containers. In Afterbirth using this with the? Treasure Map floor layout , Compass map icons or Blue Map secret room locations. Unlock this item by beating Krampus Krampus is unlocked by taking 20 devil deal items.
However, If you also have flying you will always take damage. Soy Milk can lead to interesting synergies. Half hearts heal a whole heart and full hearts heal 2 red hearts. If you get hit while Cursed eye is a solid black colour you are guaranteed to be teleported to another random room on the floor.
If you get hit in either of the other 2 states you will not be teleported. Unlock this item by beating all bosses and completing all post-it note marks in hard mode with The Lost character. Flies spawned from a Mulligan dying.
Dead Bird then Box of Friends will cause it to spawn but won't create duplicates. Mom's Foot boss counts as an explosion and is therefore prevented by Host Hat. The longer the button is held the faster Gurdy will fling itself across the screen. Every 6 coins Bumbo will evolve to a new form except for level 4 which takes 12 coins. Bumbo gains a body and crawls around the room, sometimes dropping random pickups.
Bumbo no longer fires tears but instead will chase enemies slowly and deal contact damage. It will also sometimes randomly drop bombs. Fetus, this item will also cycle through random Bomb Modifiers e. Butt Bombs, Hot Bombs. In the burst of tears is a kidney stone which deals a lot of damage. This tear turns enemies to gold for a few seconds and causes them to drop coins if killed while golden similar to the Midas' Touch item.
The priority list of what will drop from champion enemies in order is as follows:. It stops moving while Isaac is firing tears and upon releasing the fire button, King Baby will teleport back to your location. One exception to this is if you are playing as Lazarus or have Lazarus' Rags - you will respawn in the same room and get the kill. This can make it confusing while navigating the room.
This mechanic is very useful on Greed and Greedier modes. Spoon Bender will give them a homing effect. After dealing enough damage it will eventually disappear. Basement 1, Cathedral, Sheol etc. For example if the spawned boss leaves creep, it can damage Isaac.
Unlock this item by defeating Delirium for the first time on any character. Fetus, Tech X or Loki's Horns. Unlock this item by picking up any 3 of these items in a single run: Using the box again will put the picked up items back on the floor again, allowing you to move things between rooms. First it will drop all items currently inside the box and secondly will then pick up the current room's contents. Based on the Steam Workshop mod created by by Scayze and Ashkait.
Also summons a blue crosshair which can be moved around freely. After a few seconds, the crosshair will disappear, and the Ghost will do certain things based on what you targeted:.
Brings them to Isaac. Works in shops and devil deals as well, allowing you to take them for no cost. Based on the Steam Workshop mod created by Jean-Alphonse. Based on the Steam Workshop mod created by electoon and Erfly. Based on the Steam Workshop mod created by Scayze and Ashkait. Based on the Steam Workshop mod created by Merlo. Doing so will cause it to increase in size, and also increase their damage and the damage of the burst tears. Based on the Steam Workshop mod created by Ratlah.
Based on the Steam Workshop mod created by Niro. Based on the Steam Workshop mod created by Strawrat and Aczom. Based on the Steam Workshop mod created by Amethyst. Based on the Steam Workshop mod created by Maddogs. Unlock this item by defeating Mom's Heart on hard mode as The Forgotten. Enemies are frozen in place while touching the yellow ring. The first piece drops by beating the first floor boss within 1 minute then bombing the shadow in the first room.
The second piece drops after beating the Boss Rush as long as you are holding the first Broken Shovel piece see previous 2 items for full details. When taking damage, Isaac has a chance to deal damage to the entire room in a Necronomicon style effect.
Dying in a sacrifice room while holding this trinket will reveal a puzzle piece on the death screen. Finding all the puzzle pieces will help you to reveal the final secret, unlocking the hidden character 'The Lost'. This essentially means you are sacrificing your heart drops for a higher chance of all other pickups. In Afterbirth dying with this trinket causes you to respawn as The Lost character and dying in a sacrifice room while holding this trinket will now unlock the Lost character.
Unlock this item by blowing up 20 shop keepers this includes the ones in the secret room. With poison effects, the damage over time poison will last for much longer. Unlock this trinket by donating coins to the Greed Donation Machine. Krampus Head can still spawn. Each tick of poison damage is equal to your normal tear damage.
If it does, it will drop a random trinket, coin, heart and key. Based on the Steam Workshop mod created by Eufuu. Based on the Steam Workshop mod created by Ink Tears.